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Nimesulide EP Impurity A

 

Nimesulide EP Impurity A

Product Details of 'Nimesulide EP Impurity A'
Catalog Number DI-T-92564
Category Impurities
CAS Number 51765-56-1
Molecular Weight 353.31 g/mol
Molecular Formula C13H11N3O7S
Application Notes 4?,6?-Dinitro-2?-phenoxymethanesulfonanilide, is an impurity of the drug Nimesulide (N477500), which is an antiinflammatory agent. Preferentially inhibits COX-2 over COX-1. Suppresses chemical-induced carcinogenesis in mice and rats. Inhibits LPS-induced TNF-alpha production
References Pairet, M., et al.: Inflamm. Res., 47, S93 (1998), Fukutake, M., et al.: Carcinogenesis, 19, 1939 (1998), Okajima., E., et al.: Cancer Res., 58, 3028 (1998), Azab, A., et al.: Life Sci., 63, 323 (1998)
 
 
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Nimesulide EP Impurity A


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