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Amitriptyline N-oxide EP Impurity E




Catalog No. : DI-EN-00030
CAS Number : 24755-73-5
Molecular Weight : 232.32
Molecular Formula : C18H16
Synonym : Donadine; 10,11-Dihydro-5-(2-propenylidene)-5H-dibenzo[a,d]cycloheptene; 5-Allylidene-10,11-dihydro-5H-dibenzo[a,d]cycloheptene; 10,11-Dihydro-5-(2-propen-1-ylidene)-5H-dibenzo[a,d]cycloheptene; 11-prop-2-enylidene-5,6-dihydrodibenzo[2,1-b:2',1'-f][7]annu
Application Notes : 5-Allylidene-10,11-dihydro-5H-dibenzo[a,d][7]annulene is an impurity of Nortriptyline and Amitriptyline, both of which are antidepressant.
References :Hale, J. L., et al.: Anal. Profiles Drug Subs., 1, 233 (1972); Rubin, E.H., et al.: J. Clin. Psychiatry, 46, 418 (1985); Blessel, K.W., et al.: Anal. Profiles Drug Subs., 3, 127 (1974); Tobe, A., et al.: Arzneim.-Forsch., 31, 1278 (1981)