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3-Descyano Febuxostat Ethyl Ester

Catalog No. : DI-T-62866
CAS Number : 144060-97-9
Molecular Weight : 319.42
Molecular Formula : C17H21NO3S
Synonym : Ethyl 4‐methyl‐2‐[4‐(2‐methylpropoxy)phenyl]‐1,3‐ thiazole‐5‐carboxylate
Application Notes : 3-Descyano Febuxostat Ethyl Ester is an impurity of Febuxostat, a xanthine oxidase/xanthine dehydrogenase inhibitor. Used for treatment of hyperuricemia and chronic gout. 40-120 mg/day febuxostat was proven effective in lowering serum urate levels when administered to manage hyperuricemia in patients with gout.
References :Vallu, V., et. al.: Anal. Chem. Indian J., 14, 339 (2014); Osada, Y., et al.: Eur. J. Pharmacol., 241, 183 (1993); Okamoto, K., et al.: J. Biol. Chem., 278, 1848 (2003)