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2-Methyl Simvastatin ( Diasteroisomers)




Catalog No. : DI-T-58631
CAS Number : 774611-54-0
Molecular Weight : 432.59
Molecular Formula : C26H40O5
Synonym : 2,2-Dimethyl-(1S,3R,7S,8S,8aR)-1,2,3,7,8,8a-Hexahydro-3,7-dimethyl-8-[2-[(2R,4R)-tetrahydro-4-hydroxy-5-methyl-6-oxo-2H-pyran-2-yl]ethyl]-1-naphthalenyl Ester Butanoic Acid
Application Notes : 2-Methyl Simvastatin is an impurity of Simvastatin , a competitive inhibitor of HMG-CoA reductase.
References :Andelija, M., et. al.: J. Liq. Chromatogr. R. T., 32, 874 (2009); Hoffman, W.F., et al.: J. Med. Chem., 29, 849 (1986); Mol, M.J., et al.: Lancet, 2, 936 (1986)