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4-[[3-(4-Methylphenyl)-3-oxo-1-(trifluoromethyl)propylidene]amino]benzenesulfonamide




Catalog No. : DI-T-58630
CAS Number : 1061214-09-2
Molecular Weight : 384.37
Molecular Formula : C17H15F3N2O3S
Synonym : 4-[(Z)-[1,1,1-trifluoro-4-(4-methylphenyl)-4- oxobutan-2-ylidene]amino]benzene-1-sulfonamide
Application Notes : 4-[[3-(4-Methylphenyl)-3-oxo-1-(trifluoromethyl)propylidene]amino]benzenesulfonamide, is an impurity of Celecoxib , which is a selective cyclooxygenase-2 (COX-2) inhibitor, an anti-inflammatory agent. It is also used in treatment of familial adenomatous polyposis.
References :Simon, L.S., et al.: Arthritis Rheum., 41, 1591 (1998), Silverstein, F.E., et al.: J. Am. Med. Assoc., 284, 1247 (2000),