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cis-Entacapone-3'-sulfate Sodium Salt




Catalog No. : DI-T-21652
CAS Number : 158069-74-0
Molecular Weight : 407.33
Molecular Formula : C14H14N3NaO8S
Synonym : (Z)nitro-5-(sulfooxy)phenyl]-2-propenamide Sodium Salt;sodium (E)-5-(2-cyano-3-(diethylamino)-3-oxoprop-1-en-1-yl)-2-hydroxy-3-nitrophenyl sulfate
Application Notes : (Z)-Entacapone-3-sulfate is a metabolite of Entacaponec , a peripherally acting inhibitor of catechol-O-methyl transferase (COMT), an enzyme involved in the metabolism of catecholamine neurotransmitters and related drugs. Antiparkinsonian.
References :Karlsson, M., et al.: J. Pharm. Biomed. Anal., 10, 593 (1992); Nissinen, E., et al.: Arch. Pharmacol., 346, 262 (1992); Wikberg, T., et al.: Eur. J. Drug Metab. Pharmacokinet., 18, 359 (1993); Wikberg, T. et al.: Eur. J. Drug Metab. Pharmacokinet., 18, 35