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3-Piperazinylmethyl-5,5-dimethylhydantoin




Catalog No. : DI-T-20295
CAS Number : 879062-90-5
Molecular Weight : 226.28
Molecular Formula : C10H18N4O2
Synonym : 5,5-Dimethyl-3-(1-piperazinylmethyl)-2,4-imidazolidinedione;5,5-dimethyl-3-(piperazin-1-ylmethyl)imidazolidine-2,4-dione
Application Notes : 3-Piperazinylmethyl-5,5-dimethylhydantoin is a derivative of 5,5-Dimethylhydantoin . 3-Piperazinylmethyl-5,5-dimethylhydantoin is also part of a group of small molecules that have the ability to reversibly inhibit Protein Arginine Deiminase (PAD4), which can potentially be used to treat inflammatory bowel disease and cancer.
References :Chumanevich, A., et al.: Am. J. Physiol-Endoc. M., 300, G929 (2011); Wang, Y., et al.: J. Biol. Chem., 287, 25941 (2012); Wei, L., et al.: J. Med. Chem., 56, 1715 (2013)