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4-Desmethyl Istradefylline




Catalog No. : DI-T-16260
CAS Number : 160434-48-0
Molecular Weight : 370.4
Molecular Formula : C19H22N4O4
Synonym : (E)-1,3-Diethyl-3,7-dihydro-8-[2-(4-hydroxy-3-methoxyphenyl)ethenyl]-7-methyl-1H-purine-2,6-dione
Application Notes : 4-Desmethyl Istradefylline is an impurity of Istradefylline , a selective A(2A) antagonist used in the treatment of Parkinsonís disease. 4-Desmethyl Istradefylline have also been shown to exhibit inhibitory potency towards adenosine A2A receptors and is classified as its an adenosine A2A receptor antagonist. ;Impurity in commercial preparations of Istradefylline
References :Jorg, M., et al.: Bioorg. Med. Chem. Lett., 23, 3427 (2013);