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Indomethacin Impurity G




Catalog No. : DI-P-08095
CAS Number : 402849-26-7
Molecular Weight : 392.24
Molecular Formula : C19H15Cl2NO4
Synonym : [1-(3,4-Dichlorobenzoyl)-5-methoxy-2-methyl-1H-indol-3-yl]acetic Acid; 1-(3,4-Dichlorobenzoyl)-5-methoxy-2-methyl-1H-indol-3-acetic Acid; Indomethacin Impurity G; Indomethacin EP Impurity G
Application Notes : 3-Chloroindomethacin (Indomethacin EP Impurity G) is an impurity of Indomethacin (I641000) which inhibits cyclooxygenase (IC50=0.1uM) selectively over liposygenases (IC50=100uM for 5-,12- and 15-LO).
References :Salari, H., et al.: Prostagland. Leukotrienes Med., 13, 53 (1984), Lehmann, J.M., et al.: J. Biol. Chem., 272, 3406 (1997)