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Silodosin Impurity B




Catalog No. : DI-O-32152
CAS Number : 885340-13-6
Molecular Weight : 477.22
Molecular Formula : C25H30F3N3O3
Synonym : Silodosin Impurity 2 HCl;1-(3-hydroxypropyl)-5-[(2R)-2-({2-[2-(2,2,2-trifluoroethoxy)phenoxy]-ethyl}amino)propyl]-2,3-dihydro-1H-indole-7-carbonitrile ; ; 1H-Indole-7-carbonitrile, 2,3-dihydro-1-(3-hydroxypropyl)-5-[(2R)-2-[[2-[2-(2,2,2-trifluoroethoxy) phenoxy]ethyl]aMino]propyl];CS-T-53128
Application Notes : An impurity in the synthesis of Silodosin, an a1a-adrenoceptor antagonist. It is used in treatment of benign prostatic hypertophy.
References :Barve, I. et al.: Tetra., 69, 2834 (2013); Shibata, K., et al.: Mol. Pharmacol., 48, 250 (1995), Murata, S., et al.: J. Urol., 164, 578 (2000)