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Ibuprofen Sorbitol Ester (Mixture of Diastereomers)




Catalog No. : DI-O-11260
CAS Number : NA
Molecular Weight : 370.44
Molecular Formula : C19H30O7
Synonym : (2S,3R,4R,5R)-2,3,4,5,6-pentahydroxyhexyl 2-[4-(2- methylpropyl)phenyl]propanoate
Application Notes : Ibuprofen Sorbitol Ester is an impurity of ibuprofen (rac, I140000) which is a selective cyclooxygenase inhibitor. It inhibits PGH synthase-1 and PGH synthase-2 with comparable potency.
References :Busson, M., et al.: J. Int. Med Res., 14, 53 (1986), Meade, E.A., et al.: J. Biol. Chem., 268, 6610 (1993), Davies, N.M., et al.: Clin. Pharmacokinet., 34, 101 (1998)